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  • Interstitial macrophages may play role in severe COVID-19

    The intense response of interstitial macrophages in the lungs of a COVID-19 patient may offer clues to why SARS-CoV-2 infections become severe in some people, researchers reported in the Journal of Experimental Medicine. When the cells become overwhelmed by the viral infection, their heightened inflammatory response may lead to the development of pneumonia, researchers noted. Immunologist Jose Ordovas-Montanes, who was not part of the research, said the findings may help scientists better understand the role of these cells. Science News (4/10) Learn More

  • Study finds skin bacteria lead to post-surgical infections

    A study of patients who had undergone spinal procedures showed that surgical infections may largely be caused by bacteria that are already in the skin microbiome. Scientists analyzed microbes that caused wound infections in 14 of the patients and found that 12 of the cases involved bacteria present on their skin before they had surgery. New Scientist (4/10) Learn More

  • Post-hospitalization COVID-19 deaths higher in rural areas

    COVID-19 patients in rural areas were 22% more likely to die following a hospital stay than people in urban areas, with disparities persisting even after vaccines became available, a Mayo Clinic analysis showed. The study published in the journal Open Forum Infectious Diseases also found that rural patients tend to be older and have higher rates of conditions such as heart failure, obesity, depression, chronic obstructive pulmonary disease and substance use that are tied to poor outcomes. Axios (4/9) Learn More

  • AI helps streamline physicians' message volume

    Kaiser Permanente investigators reported in a JAMA Network Open research letter that patient messages can be handled more efficiently with the use of artificial intelligence technology. They detailed a strategy that uses real-time natural language processing algorithms to categorize messages and forward them to appropriate individuals, freeing up valuable time for physicians. They noted that nearly one-third of messages could be resolved before entering a physician's inbox. Fierce Healthcare (4/9) Learn More

  • Web tool helps people determine if they need a statin

    A study published in JACC found that a web-based tool helped most people determine if they needed a statin and aided them in using the medication correctly without a prescription. LDL cholesterol decreased by 35.5% over six months for trial participants. MedPage Today (free registration) (4/8) Learn More

  • De novo tag granted to antibacterial tech from Orthobond

    The FDA has given de novo approval to Orthobond's Ostaguard antibacterial technology. The non-eluting coating is intended to eliminate the bacteria that may contaminate medical device surfaces. MassDevice (Boston) (4/8) Learn More

  • Impella CP use for STEMI, cardiogenic shock may reduce mortality risk

    The Impella CP microaxial flow pump combined with standard care was associated with a reduced mortality risk for patients with ST-elevation myocardial infarction and cardiogenic shock, when compared with standard care alone, according to data from the DanGer Shock trial presented at ACC.24 and published in The New England Journal of Medicine. "Overall, we have more complications, but we also save lives," said lead author Dr. Jacob Møller. Medscape (4/9) Learn More

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